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Cat. No. | Product Name | Target | Signaling Pathways |
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T3598 |
JNK-IN-7
JNK inhibitor |
JNK | MAPK |
JNK-IN-7 (JNK inhibitor) 是 JNK 抑制剂,抑制 JNK1、JNK2和 JNK3,IC50分别为 1.5、2 和 0.7 nM。 | |||
T74817 | JNK3 inhibitor-7 | ||
JNK3inhibitor-7 是一种有效的口服活性JNK3抑制剂,能穿过血脑屏障,其对JNK3、JNK2、JNK1的IC50值分别为53、973、1039 nM。该化合物表现出显著的神经保护作用,并具备研究阿尔茨海默病(AD)潜力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37452 |
Stephacidin B
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Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc... |